lirilumab

Ligand id: 9310

Name: lirilumab

Bioactivity Comments
Avidities of 1-7F9 (lirilumab) for KIR2DL1 and KIR2DL3 are 0.43 and 0.025nM respectively, assessed by Biacore analysis [1]. In preclinical functional studies 1-7F9 provides stable blockade of KIR inhibitory signals and boosts NK-mediated killing in vitro and in vivo [1]