(B7-33)H2   Click here for help

GtoPdb Ligand ID: 9321

Comment: H2 relaxin B-chain-only analogue, B7-33, which was shown to bind to RXFP1 and preferentially activate the pERK pathway over cAMP in cells that endogenously expressed RXFP1.
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
RXFP1 Hs Agonist Full agonist 5.5 pKi - 1-2
pKi 5.5 [1-2]