GSK3050002   Click here for help

GtoPdb Ligand ID: 9623

Synonyms: E6071 | KANAb071
Immunopharmacology Ligand
Compound class: Antibody
Comment: GSK3050002 is a humanized IgG1κ antibody with high binding affinity to the human chemokine, CCL20. This biologic is being developed by GlaxoSmithKline in collaboration with Morphotek, based on a non-humanized antibody originally identified by KAN Research Institute, Inc., a subsidiary of Eisai Co., Ltd.
Selectivity at ligand targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CCL20 Primary target of this compound Hs Antibody Binding 10.3 pKd - 1
⤷ pKd 10.3 (Kd 4.8x10-11 M) [1]
Description: Binding to human CCL20.