Ligand id: 1884

Name: PGF

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 12
Topological polar surface area 97.99
Molecular weight 354.24
XLogP 3.2
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Dinoprost is used clinically to induce labor and abortion.
Mechanism Of Action and Pharmacodynamic Effects
Dinoprost activates the prostaglandin F receptor (FP receptor; a Gq coupled GPCR) which induces uterine contractions.