Ligand id: 2790

Name: doxercalciferol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 40.46
Molecular weight 412.33
XLogP 8.69
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of secondary hyperparathyroidism and metabolic bone disease.
Mechanism Of Action and Pharmacodynamic Effects
Synthetic analogue of vitamin D, acting as an agonist at the vitamin D receptor, which has the effect of suppressing parathyroid synthesis and secretion.