Ligand id: 4783

Name: guanidine

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 0
Topological polar surface area 75.89
Molecular weight 59.05
XLogP -0.65
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Guanidine may be used to manage symptoms of muscle weakness and fatigue suffered by patients with myasthenic syndrome (Eaton-Lambert type).
Mechanism Of Action and Pharmacodynamic Effects
Guanidine appears to enhance the release of acetylcholine following a nerve impulse.