IFN-κ   Click here for help

GtoPdb Ligand ID: 4969

Synonyms: interferon kappa
Immunopharmacology Ligand
Comment: IFN-κ is a type I IFN.
Species: Human
Immunopharmacology Comments
IFN-κ is produced by human keratinocytes [1-2]. Like other type I IFNs, IFN-κ binds the IFN-α/β receptor (IFNAR), a dimeric receptor that consists of protein chains encoded by the IFNAR1 and IFNAR2 genes, and induces expression of proteins containing ISRE or GAS transcription elements.