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Synonyms: interferon alpha-II-1 | interferon omega-1
Compound class: Endogenous peptide in human, mouse or rat
Comment: IFN-ω is a type I IFN. In humans, only one functional form has been characterised; however, several pseudogenes are described.
|IFN-ω is secreted by leukocytes at the site of viral infection or by tumors. Like other type I IFNs, IFN-ω binds the IFN-α/β receptor (IFNAR), a dimeric receptor that consists of protein chains encoded by the IFNAR1 and IFNAR2 genes, and induces expression of proteins containing ISRE or GAS transcription elements.|