Abbreviated name: TNFSF1
Synonyms: LTα | TNFβ
Compound class:
Endogenous peptide in human, mouse or rat
Comment: LTA (TNFβ) is a pro-inflammarory cytokine mediating a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is required during embryonic development of lymphoid organs.
Species: Human
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Immunopharmacology Comments |
LTA (TNFβ) is a lymphocyte produced cytokine of the tumor necrosis factor family. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, and is required during embryonic development of lymphoid organs. Genetic variants are associated with non-Hodgkin's lymphoma, and psoriatic arthritis. |
Immunopharmacology Disease | |||
Disease | X-Refs | Comment | References |
Lymphoma, non-hodgkin, familial |
Disease Ontology:
DOID:0060060 OMIM: 605027 |
Approved therapy for this indication. | |
Psoriatic arthritis |
Disease Ontology:
DOID:9008 |
Approved therapy for PsA. |