Synonyms: bimekizumab-bkzx | Bimzelx® | CA028_0496 | CDP4940 | gL7gH9 | UCB-4940 | UCB4940 | Zu-G1
bimekizumab is an approved drug (EMA (2021), FDA (2023))
Compound class:
Antibody
Comment: Bimekizumab (UCB4940) is a rat-derived humanized monoclonal antibody that simultaneously targets IL-17A and IL-7F (dual antagonist), with potential for controlling autoimmune conditions mediated by these proinflammatory cytokines. Safety, pharmacokinetics and clinical efficacy of bimekizumab in mild psoriasis were reported in [2]. Claimed in patent WO2008047134 as CA028_0496 [1].
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Immunopharmacology Comments |
Bimekizumab is a rat-derived humanized anti-IL-17A/L-7F mAb that has potential for controlling autoimmune conditions mediated by these proinflammatory cytokines. |