Ligand id: 9729

Name: olamkicept

Immunopharmacology Comments
Olamkicept is a selective inhibitor of the IL-6 proinflammatory pathway. It blocks trans signaling that occurs via the soluble IL-6R (sIL-6R) and this action is effective against Crohn's disease and experimental colitis in vivo [1].
Immunopharmacology Disease
Disease X-Refs Comment References
Ulcerative colitis Disease Ontology: DOID:8577
OMIM: 266600
Orphanet: ORPHA771
Phase 2 clinical candidate for active UC- see NCT03235752.