ibalizumab

Ligand id: 10208

Name: ibalizumab

References
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Inhibition of HIV infection by a novel CD4 domain 2-specific monoclonal antibody. Dissecting the basis for its inhibitory effect on HIV-induced cell fusion.
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A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4.
Sci Rep, 7: 46733. [PMID:28429756]
3. Emu B, Fessel J, Schrader S, Kumar P, Richmond G, Win S, Weinheimer S, Marsolais C, Lewis S. (2018)
Phase 3 Study of Ibalizumab for Multidrug-Resistant HIV-1.
N. Engl. J. Med., 379 (7): 645-654. [PMID:30110589]
4. Iacob SA, Iacob DG. (2017)
Ibalizumab Targeting CD4 Receptors, An Emerging Molecule in HIV Therapy.
Front Microbiol, 8: 2323. [PMID:29230203]
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Antiretroviral activity of the anti-CD4 monoclonal antibody TNX-355 in patients infected with HIV type 1.
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