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Compound class: Peptide or derivative
Comment: Casoxin C is a bioactive peptide derived from a tryptic digest of bovine κ-casein . It shares sequence homology with complement peptide C3a(70-77) and acts as an agonist of the C3a complement peptide receptor.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Takahashi M, Moriguchi S, Suganuma H, Shiota A, Tani F, Usui H, Kurahashi K, Sasaki R, Yoshikawa M. (1997)
Identification of casoxin C, an ileum-contracting peptide derived from bovine kappa-casein, as an agonist for C3a receptors.
Peptides, 18 (3): 329-36. [PMID:9145417]
2. Yoshikawa M. (2015)
Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects.
Peptides, 72: 208-25. [PMID:26297549]