Synonyms: POL7080 | RG-7929 | RG7929 | RO-7033877 | RO7033877
Compound class:
Peptide or derivative
Comment: Murepavadin is a cyclic β hairpin peptidomimetic based on the cationic antimicrobial peptide protegrin I. It targets the outer membrane of Gram-negative pathogens [1].
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References |
1. Brown DG. (2016)
Drug discovery strategies to outer membrane targets in Gram-negative pathogens. Bioorg Med Chem, 24 (24): 6320-6331. [PMID:27178386] |
2. Martin-Loeches I, Dale GE, Torres A. (2018)
Murepavadin: a new antibiotic class in the pipeline. Expert Rev Anti Infect Ther, 16 (4): 259-268. [PMID:29451043] |