GnRH II   Click here for help

GtoPdb Ligand ID: 1164

Synonyms: gonadoliberin II | gonadoliberin-2 | gonadotropin-releasing hormone II | LH-RH II | luliberin II | luteinizing hormone-releasing hormone II
Species: Human
Click here for help
References
1. Fister S, G√ľnthert AR, Aicher B, Paulini KW, Emons G, Gr√ľndker C. (2009)
GnRH-II antagonists induce apoptosis in human endometrial, ovarian, and breast cancer cells via activation of stress-induced MAPKs p38 and JNK and proapoptotic protein Bax.
Cancer Res, 69 (16): 6473-81. [PMID:19638591]
2. Lu ZL, Coetsee M, White CD, Millar RP. (2007)
Structural determinants for ligand-receptor conformational selection in a peptide G protein-coupled receptor.
J Biol Chem, 282 (24): 17921-9. [PMID:17452338]
3. Millar R, Lowe S, Conklin D, Pawson A, Maudsley S, Troskie B, Ott T, Millar M, Lincoln G, Sellar R et al.. (2001)
A novel mammalian receptor for the evolutionarily conserved type II GnRH.
Proc Natl Acad Sci USA, 98 (17): 9636-41. [PMID:11493674]
4. Millar RP, Lu ZL, Pawson AJ, Flanagan CA, Morgan K, Maudsley SR. (2004)
Gonadotropin-releasing hormone receptors.
Endocr Rev, 25 (2): 235-75. [PMID:15082521]
5. Stewart AJ, Sellar R, Wilson DJ, Millar RP, Lu ZL. (2008)
Identification of a novel ligand binding residue Arg38(1.35) in the human gonadotropin-releasing hormone receptor.
Mol Pharmacol, 73 (1): 75-81. [PMID:17942747]