[Phe13,Tyr19]MCH   Click here for help

GtoPdb Ligand ID: 1297

Synonyms: [Phe13,Tyr19]-melanin-concentrating hormone
Comment: Synthetic analogue of MCH
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1. Chambers J, Ames RS, Bergsma D, Muir A, Fitzgerald LR, Hervieu G, Dytko GM, Foley JJ, Martin J, Liu WS et al.. (1999)
Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1.
Nature, 400 (6741): 261-5. [PMID:10421367]
2. Kokkotou EG, Tritos NA, Mastaitis JW, Slieker L, Maratos-Flier E. (2001)
Melanin-concentrating hormone receptor is a target of leptin action in the mouse brain.
Endocrinology, 142 (2): 680-6. [PMID:11159839]
3. Sailer AW, Sano H, Zeng Z, McDonald TP, Pan J, Pong SS, Feighner SD, Tan CP, Fukami T, Iwaasa H et al.. (2001)
Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R.
Proc Natl Acad Sci USA, 98 (13): 7564-9. [PMID:11404457]
4. Suply T, Della Zuana O, Audinot V, Rodriguez M, Beauverger P, Duhault J, Canet E, Galizzi JP, Nahon JL, Levens N et al.. (2001)
SLC-1 receptor mediates effect of melanin-concentrating hormone on feeding behavior in rat: a structure-activity study.
J Pharmacol Exp Ther, 299 (1): 137-46. [PMID:11561073]
5. Wang S, Behan J, O'Neill K, Weig B, Fried S, Laz T, Bayne M, Gustafson E, Hawes BE. (2001)
Identification and pharmacological characterization of a novel human melanin-concentrating hormone receptor, mch-r2.
J Biol Chem, 276 (37): 34664-70. [PMID:11459838]