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Synonyms: 5',5'''-diadenosine tetraphosphate | adenosyl-P4 | Ap4A | diadenosine tetraphosphate
Compound class: Metabolite or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Castro E, Pintor J, Miras-Portugal MT. (1992)
Ca(2+)-stores mobilization by diadenosine tetraphosphate, Ap4A, through a putative P2Y purinoceptor in adrenal chromaffin cells.
Br J Pharmacol, 106 (4): 833-7. [PMID:1393282]
2. Kennedy C, Qi AD, Herold CL, Harden TK, Nicholas RA. (2000)
ATP, an agonist at the rat P2Y(4) receptor, is an antagonist at the human P2Y(4) receptor.
Mol Pharmacol, 57 (5): 926-31. [PMID:10779375]
3. Marteau F, Le Poul E, Communi D, Communi D, Labouret C, Savi P, Boeynaems JM, Gonzalez NS. (2003)
Pharmacological characterization of the human P2Y13 receptor.
Mol Pharmacol, 64 (1): 104-12. [PMID:12815166]
4. Patel K, Barnes A, Camacho J, Paterson C, Boughtflower R, Cousens D, Marshall F. (2001)
Activity of diadenosine polyphosphates at P2Y receptors stably expressed in 1321N1 cells.
Eur J Pharmacol, 430 (2-3): 203-10. [PMID:11711032]