relaxin-1   Click here for help

GtoPdb Ligand ID: 1988

Synonyms: H1 relaxin
Species: Human
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View more information in the IUPHAR Pharmacology Education Project: relaxin

1. Bathgate RA, Lin F, Hanson NF, Otvos L, Guidolin A, Giannakis C, Bastiras S, Layfield SL, Ferraro T, Ma S, Zhao C, Gundlach AL, Samuel CS, Tregear GW, Wade JD. (2006)
Relaxin-3: Improved Synthesis Strategy and Demonstration of Its High-Affinity Interaction with the Relaxin Receptor LGR7 Both In Vitro and In Vivo.
Biochemistry, 45: 1043-1053. [PMID:16411781]
2. Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RA, Hsueh AJ. (2003)
H3 relaxin is a specific ligand for LGR7 and activates the receptor by interacting with both the ectodomain and the exoloop 2.
J Biol Chem, 278 (10): 7855-62. [PMID:12506116]