[125I]INSL5 (human)   Click here for help

GtoPdb Ligand ID: 2001

Synonyms: [125I]insulin-like peptide 5
 Ligand is labelled  Ligand is radioactive
Compound class: Peptide
Comment: Fully active INSL5 is a heterodimer of the B chain and the A chain linked by two disulfide bonds, the first between B chain (residue 29) and A chain (residue 122), and the second between B chain (residue 41) and A chain (residue 135). For structural information for the radioactive ligand please see the ligand pages for the non-radiolabelled form and its subunits
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References
1. Liu C, Kuei C, Sutton S, Chen J, Bonaventure P, Wu J, Nepomuceno D, Kamme F, Tran DT, Zhu J et al.. (2005)
INSL5 is a high affinity specific agonist for GPCR142 (GPR100).
J Biol Chem, 280 (1): 292-300. [PMID:15525639]