Ligand id: 2370

Name: dehydroepiandrosterone

Abbreviated name: DHEA

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 37.3
Molecular weight 288.21
XLogP 3.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Maksay G, Laube B, Betz H. (2001)
Subunit-specific modulation of glycine receptors by neurosteroids.
Neuropharmacology, 41 (3): 369-76. [PMID:11522328]
2. Rose KA, Stapleton G, Dott K, Kieny MP, Best R, Schwarz M, Russell DW, Bj√∂rkhem I, Seckl J, Lathe R. (1997)
Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7alpha-hydroxy dehydroepiandrosterone and 7alpha-hydroxy pregnenolone.
Proc. Natl. Acad. Sci. U.S.A., 94 (10): 4925-30. [PMID:9144166]