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Synonyms: α-mammal toxin Lqh2 | Lqh II | LqhII | LqTx-2
Compound class:
Peptide or derivative
Comment: Toxin from Leiurus quinquestriatus hebraeus (Yellow scorpion).
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| References |
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1. Leipold E, Lu S, Gordon D, Hansel A, Heinemann SH. (2004)
Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3. Mol Pharmacol, 65 (3): 685-91. [PMID:14978247] |
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2. Rogers JC, Qu Y, Tanada TN, Scheuer T, Catterall WA. (1996)
Molecular determinants of high affinity binding of alpha-scorpion toxin and sea anemone toxin in the S3-S4 extracellular loop in domain IV of the Na+ channel alpha subunit. J Biol Chem, 271 (27): 15950-62. [PMID:8663157] |
