- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: phosphatidylinositol 3,5-bisphosphate | PI(3,5)P2
Compound class: Metabolite or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Cang C, Bekele B, Ren D. (2014)
The voltage-gated sodium channel TPC1 confers endolysosomal excitability.
Nat Chem Biol, 10 (6): 463-9. [PMID:24776928]
2. Dong XP, Shen D, Wang X, Dawson T, Li X, Zhang Q, Cheng X, Zhang Y, Weisman LS, Delling M et al.. (2010)
PI(3,5)P(2) controls membrane trafficking by direct activation of mucolipin Ca(2+) release channels in the endolysosome.
Nat Commun, 1: 38. [PMID:20802798]
3. Wang X, Zhang X, Dong XP, Samie M, Li X, Cheng X, Goschka A, Shen D, Zhou Y, Harlow J et al.. (2012)
TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes.
Cell, 151 (2): 372-83. [PMID:23063126]