europium-labelled relaxin-3-B/INSL5 A chimera   Click here for help

GtoPdb Ligand ID: 4374

Synonyms: Eu-R3/I5 | europium-labelled H3-B/INSL5 A chimera
 Ligand is labelled
Compound class: Peptide
Comment: Europium-labelled relaxin-3-B/INSL5 A chimera is a chemiluminescent probe analogue of the ligand relaxin-3/INSL5 chimera. It consists of 2 subunits: the B chain subunit of human relaxin-3 and the A chain subunit of human INSL5.
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References
1. Haugaard-Kedström LM, Shabanpoor F, Hossain MA, Clark RJ, Ryan PJ, Craik DJ, Gundlach AL, Wade JD, Bathgate RA, Rosengren KJ. (2011)
Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3.
J Am Chem Soc, 133 (13): 4965-74. [PMID:21384867]
2. Shabanpoor F, Akhter Hossain M, Ryan PJ, Belgi A, Layfield S, Kocan M, Zhang S, Samuel CS, Gundlach AL, Bathgate RA et al.. (2012)
Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1.
J Med Chem, 55 (4): 1671-81. [PMID:22257012]