CX<sub>3</sub>CL1 | Ligand page | IUPHAR/BPS Guide to PHARMACOLOGY

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Ligands
CX₃CL1 (Rat)

CX₃CL1

GtoPdb Ligand ID: 4469

Compound class: Endogenous peptide in human, mouse or rat

Comment: This is the rat homologue of human CX3CL1 (fractalkine). It is the endogenous ligand for CX3CR1, which mediates both leukocyte migration and adhesion [1].

Species: Rat

Summary
Biological activity
References
Structure
Similar ligands
Immunopharmacology

References
1. Imai T, Hieshima K, Haskell C, Baba M, Nagira M, Nishimura M, Kakizaki M, Takagi S, Nomiyama H, Schall TJ et al.. (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell, 91 (4): 521-30. [PMID:9390561]

References

1. Imai T, Hieshima K, Haskell C, Baba M, Nagira M, Nishimura M, Kakizaki M, Takagi S, Nomiyama H, Schall TJ et al.. (1997)
Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion.
Cell, 91 (4): 521-30. [PMID:9390561]