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Synonyms: β-alanyl-L-histidine | L-carnosine
Compound class: Metabolite or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Bhardwaj RK, Herrera-Ruiz D, Eltoukhy N, Saad M, Knipp GT. (2006)
The functional evaluation of human peptide/histidine transporter 1 (hPHT1) in transiently transfected COS-7 cells.
Eur J Pharm Sci, 27 (5): 533-42. [PMID:16289537]
2. Oppermann H, Heinrich M, Birkemeyer C, Meixensberger J, Gaunitz F. (2019)
The proton-coupled oligopeptide transporters PEPT2, PHT1 and PHT2 mediate the uptake of carnosine in glioblastoma cells.
Amino Acids, 51 (7): 999-1008. [PMID:31073693]
3. Sakata K, Yamashita T, Maeda M, Moriyama Y, Shimada S, Tohyama M. (2001)
Cloning of a lymphatic peptide/histidine transporter.
Biochem J, 356 (Pt 1): 53-60. [PMID:11336635]
4. Yamashita T, Shimada S, Guo W, Sato K, Kohmura E, Hayakawa T, Takagi T, Tohyama M. (1997)
Cloning and functional expression of a brain peptide/histidine transporter.
J Biol Chem, 272 (15): 10205-11. [PMID:9092568]