L-cysteine   Click here for help

GtoPdb Ligand ID: 4782

Abbreviated name: L-Cys
PDB Ligand
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 102.12
Molecular weight 121.02
XLogP -2.58
No. Lipinski's rules broken 0
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Canonical SMILES NC(C(=O)O)CS
Isomeric SMILES N[C@H](C(=O)O)CS
InChI InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
1. Albers A, Bröer A, Wagner CA, Setiawan I, Lang PA, Kranz EU, Lang F, Bröer S. (2001)
Na+ transport by the neural glutamine transporter ATA1.
Pflugers Arch, 443 (1): 92-101. [PMID:11692272]
2. Chen X, Jhee KH, Kruger WD. (2004)
Production of the neuromodulator H2S by cystathionine beta-synthase via the condensation of cysteine and homocysteine.
J Biol Chem, 279 (50): 52082-6. [PMID:15520012]
3. Zaia KA, Reimer RJ. (2009)
Synaptic Vesicle Protein NTT4/XT1 (SLC6A17) Catalyzes Na+-coupled Neutral Amino Acid Transport.
J Biol Chem, 284 (13): 8439-48. [PMID:19147495]
4. Zerangue N, Kavanaugh MP. (1996)
Interaction of L-cysteine with a human excitatory amino acid transporter.
J Physiol (Lond.), 493 ( Pt 2): 419-23. [PMID:8782106]