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Synonyms: ABS 212 | ABS212
Compound class: Peptide or derivative
Comment: Synthetic analogue of NT(8-13)
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Hughes FM, Shaner BE, May LA, Zotian L, Brower JO, Woods RJ, Cash M, Morrow D, Massa F, Mazella J et al.. (2010)
Identification and functional characterization of a stable, centrally active derivative of the neurotensin (8-13) fragment as a potential first-in-class analgesic.
J Med Chem, 53 (12): 4623-32. [PMID:20481538]
2. Li H, Hua T, Wang W, Wu X, Miao C, Huang W, Xiao Y, Yang J, Bradley JL, Peberdy MA et al.. (2019)
The Effects of Pharmacological Hypothermia Induced by Neurotensin Receptor Agonist ABS 201 on Outcomes of CPR.
Shock, 51 (5): 667-673. [PMID:30986796]