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Synonyms: ABS 201 | ABS201 | HPI-201 | HPI201 | KK13
Compound class: Peptide or derivative
Comment: ABS-201 (a.k.a. HPI-201) is a synthetic analogue of the C-terminal hexapeptide of neurotensin (Neurotensin[8-13]) that is the essential determinant of its biological activity.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Choi KE, Hall CL, Sun JM, Wei L, Mohamad O, Dix TA, Yu SP. (2012)
A novel stroke therapy of pharmacologically induced hypothermia after focal cerebral ischemia in mice.
FASEB J, 26 (7): 2799-810. [PMID:22459147]
2. Zhao Y, Wei ZZ, Lee JH, Gu X, Sun J, Dix TA, Wei L, Yu SP. (2020)
Pharmacological hypothermia induced neurovascular protection after severe stroke of transient middle cerebral artery occlusion in mice.
Exp Neurol, 325: 113133. [PMID:31770520]