D-Ala-Lys-AMCA   Click here for help

GtoPdb Ligand ID: 5421

Synonyms: (D)-Ala-(L)-Lys-Nε-AMCA | D-Ala-Lys-N(epsilon)-7-amino-4-methylcoumarin-3-acetic acid
 Ligand is labelled
Comment: A fluorescent dipeptide
1. Gong Y, Zhang J, Wu X, Wang T, Zhao J, Yao Z, Zhang Q, Liu X, Jian X. (2017)
Specific expression of proton-coupled oligopeptide transporter 1 in primary hepatocarcinoma-a novel strategy for tumor-targeted therapy.
Oncol Lett, 14 (4): 4158-4166. [PMID:28943923]
2. Groneberg DA, Döring F, Eynott PR, Fischer A, Daniel H. (2001)
Intestinal peptide transport: ex vivo uptake studies and localization of peptide carrier PEPT1.
Am J Physiol Gastrointest Liver Physiol, 281 (3): G697-704. [PMID:11518682]
3. Kottra G, Spanier B, Verri T, Daniel H. (2013)
Peptide transporter isoforms are discriminated by the fluorophore-conjugated dipeptides β-Ala- and d-Ala-Lys-N-7-amino-4-methylcoumarin-3-acetic acid.
Physiol Rep, 1 (7): e00165. [PMID:24744852]
4. Tai W, Chen Z, Cheng K. (2013)
Expression profile and functional activity of peptide transporters in prostate cancer cells.
Mol Pharm, 10 (2): 477-87. [PMID:22950754]
5. Wenzel U, Diehl D, Herget M, Daniel H. (1998)
Endogenous expression of the renal high-affinity H+-peptide cotransporter in LLC-PK1 cells.
Am J Physiol, 275 (6 Pt 1): C1573-9. [PMID:9843719]