- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: CGP 39393 | CGP-39393 | CGP39393
desirudin is an approved drug (FDA (no history prior to 2003))
Compound class: Peptide or derivative
Comment: Desirudin is an anticoagulant. The drug is a recombinant form of hirudin (P01050), the salivary anticoagulant found in leeches.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
View more information in the IUPHAR Pharmacology Education Project: desirudin
1. Eriksson BI, Wille-Jørgensen P, Kälebo P, Mouret P, Rosencher N, Bösch P, Baur M, Ekman S, Bach D, Lindbratt S et al.. (1997)
A comparison of recombinant hirudin with a low-molecular-weight heparin to prevent thromboembolic complications after total hip replacement.
N Engl J Med, 337 (19): 1329-35. [PMID:9358126]
2. Johnson PH, Sze P, Winant RC, Hudson D, Underhill P, Lazar JB, Olsen C, Almquist R. (1991)
Structure-function and refolding studies of the thrombin-specific inhibitor hirudin.
Haemostasis, 21 Suppl 1: 41-8. [PMID:1894196]