GtoPdb Ligand ID: 650

Synonyms: [Lys]bradykinin | kallidin II | Lys-BK | Lysyl-bradykinin
Species: Human
2D Structure
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Canonical SMILES NCCCCC(C(=O)NC(C(=O)N1CCCC1C(=O)N1CCCC1C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)O)CCCN=C(N)N)Cc1ccccc1)CO)Cc1ccccc1)CCCN=C(N)N)N
Isomeric SMILES NCCCC[C@@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCN=C(N)N)Cc1ccccc1)CO)Cc1ccccc1)CCCN=C(N)N)N
InChI InChI=1S/C56H85N17O12/c57-24-8-7-18-36(58)46(76)67-37(19-9-25-63-55(59)60)51(81)73-29-13-23-44(73)53(83)72-28-11-21-42(72)49(79)65-32-45(75)66-39(30-34-14-3-1-4-15-34)47(77)70-41(33-74)52(82)71-27-12-22-43(71)50(80)69-40(31-35-16-5-2-6-17-35)48(78)68-38(54(84)85)20-10-26-64-56(61)62/h1-6,14-17,36-44,74H,7-13,18-33,57-58H2,(H,65,79)(H,66,75)(H,67,76)(H,68,78)(H,69,80)(H,70,77)(H,84,85)(H4,59,60,63)(H4,61,62,64)/t36-,37-,38-,39-,40-,41-,42-,43-,44-/m0/s1
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Stable expression of the human kinin B1 receptor in Chinese hamster ovary cells. Characterization of ligand binding and effector pathways.
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Stable expression of human kinin B1 receptor in 293 cells: pharmacological and functional characterization.
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Enzymatic properties of human aminopeptidase A. Regulation of its enzymatic activity by calcium and angiotensin IV.
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4. Hess JF, Borkowski JA, MacNeil T, Stonesifer GY, Fraher J, Strader CD, Ransom RW. (1994)
Differential pharmacology of cloned human and mouse B2 bradykinin receptors.
Mol Pharmacol, 45: 1-8. [PMID:8302267]
5. Hess JF, Derrick AW, MacNeil T, Borkowski JA. (1996)
The agonist selectivity of a mouse B1 bradykinin receptor differs from human and rabbit B1 receptors.
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Molecular characterisation of cloned bradykinin B1 receptors from rat and human.
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7. Migaud M, Durieux C, Viereck J, Soroca-Lucas E, FourniĆ©-Zaluski MC, Roques BP. (1996)
The in vivo metabolism of cholecystokinin (CCK-8) is essentially ensured by aminopeptidase A.
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8. Zini S, Fournie-Zaluski MC, Chauvel E, Roques BP, Corvol P, Llorens-Cortes C. (1996)
Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release.
Proc. Natl. Acad. Sci. U.S.A., 93 (21): 11968-73. [PMID:8876246]