chondroitin sulphate proteoglycan 3   Click here for help

GtoPdb Ligand ID: 6616

Abbreviated name: CSPG3
Synonyms: neurocan
Comment: This protein contains an immunoglobulin (Ig)-like domain that resembles the antibody variable domain, that has been coined the 'V-set domain'. The genes for all human V-set domain containing proteins are listed in HGNC gene group 590.
Species: Human
1. Kwon SK, Woo J, Kim SY, Kim H, Kim E. (2010)
Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.
J Biol Chem, 285 (18): 13966-78. [PMID:20139422]
2. Shen Y, Tenney AP, Busch SA, Horn KP, Cuascut FX, Liu K, He Z, Silver J, Flanagan JG. (2009)
PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration.
Science, 326 (5952): 592-6. [PMID:19833921]