[Cys(Et)2,7]α-CGRP (human)   Click here for help

GtoPdb Ligand ID: 693

Synonyms: [cys(Et)2,7]α-calcitonin gene-related peptide (human)
Compound class: Peptide or derivative
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
References
1. Hay DL, Christopoulos G, Christopoulos A, Poyner DR, Sexton PM. (2005)
Pharmacological discrimination of calcitonin receptor: receptor activity-modifying protein complexes.
Mol Pharmacol, 67 (5): 1655-65. [PMID:15692146]
2. Kuwasako K, Cao YN, Nagoshi Y, Tsuruda T, Kitamura K, Eto T. (2004)
Characterization of the human calcitonin gene-related peptide receptor subtypes associated with receptor activity-modifying proteins.
Mol Pharmacol, 65 (1): 207-13. [PMID:14722252]
3. Nodin C, Vauquelin G, von Mentzer B. (2005)
Cys2,7EtalphaCGRP is a potent agonist for CGRP1 receptors in SK-N-MC cells.
Biochem Pharmacol, 69 (8): 1235-40. [PMID:15794944]