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Synonyms: Actigall® | UDCA
ursodeoxycholic acid is an approved drug (UK (2003))
Compound class: Metabolite or derivative
Comment: Unfortunately ursodeoxycholic acid is found in large quantities in bear bile  and this results in the practice of 'farming' bears for bile extraction, in some east Asian countries.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Hagey LR, Crombie DL, Espinosa E, Carey MC, Igimi H, Hofmann AF. (1993)
Ursodeoxycholic acid in the Ursidae: biliary bile acids of bears, pandas, and related carnivores.
J Lipid Res, 34 (11): 1911-7. [PMID:8263415]
2. Jackson H, Solaymani-Dodaran M, Card TR, Aithal GP, Logan R, West J. (2007)
Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study.
Hepatology, 46 (4): 1131-7. [PMID:17685473]