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Synonyms: [125I]macrophage inflammatory protein-1α | [125I]MIP-1α
Compound class: Peptide or derivative
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Ben-Baruch A, Xu L, Young PR, Bengali K, Oppenheim JJ, Wang JM. (1995)
Monocyte chemotactic protein-3 (MCP3) interacts with multiple leukocyte receptors. C-C CKR1, a receptor for macrophage inflammatory protein-1 alpha/Rantes, is also a functional receptor for MCP3.
J. Biol. Chem., 270 (38): 22123-8. [PMID:7545673]
2. Gong X, Gong W, Kuhns DB, Ben-Baruch A, Howard OM, Wang JM. (1997)
Monocyte chemotactic protein-2 (MCP-2) uses CCR1 and CCR2B as its functional receptors.
J. Biol. Chem., 272 (18): 11682-5. [PMID:9115216]
3. Sarau HM, Rush JA, Foley JJ, Brawner ME, Schmidt DB, White JR, Barnette MS. (1997)
Characterization of functional chemokine receptors (CCR1 and CCR2) on EoL-3 cells: a model system to examine the role of chemokines in cell function.
J. Pharmacol. Exp. Ther., 283 (1): 411-8. [PMID:9336350]