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Synonyms: COR-005 | DG3173 | PTR-3173 | somatoprim
Compound class: Peptide or derivative
Comment: Veldoreotide (COR-005) is an investigational somatostatin analogue (SSA)  in early stage development for treatment of patients with acromegaly.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
1. Afargan M, Janson ET, Gelerman G, Rosenfeld R, Ziv O, Karpov O, Wolf A, Bracha M, Shohat D, Liapakis G et al.. (2001)
Novel long-acting somatostatin analog with endocrine selectivity: potent suppression of growth hormone but not of insulin.
Endocrinology, 142 (1): 477-86. [PMID:11145612]
2. McCarver SJ, Qiao JX, Carpenter J, Borzilleri RM, Poss MA, Eastgate MD, Miller MM, MacMillan DW. (2017)
Decarboxylative Peptide Macrocyclization through Photoredox Catalysis.
Angew. Chem. Int. Ed. Engl., 56 (3): 728-732. [PMID:27860140]
3. Shimon I, Rubinek T, Hadani M, Alhadef N. (2004)
PTR-3173 (somatoprim), a novel somatostatin analog with affinity for somatostatin receptors 2, 4 and 5 is a potent inhibitor of human GH secretion.
J. Endocrinol. Invest., 27 (8): 721-7. [PMID:15636423]