human GIP(1-30)NH2   Click here for help

GtoPdb Ligand ID: 8973

Comment: GIP(1-30)NH2 is a naturally occurring agonist of the GIP receptor [1-2].
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1. Fujita Y, Wideman RD, Asadi A, Yang GK, Baker R, Webber T, Zhang T, Wang R, Ao Z, Warnock GL et al.. (2010)
Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion.
Gastroenterology, 138 (5): 1966-75. [PMID:20138041]
2. Hansen LS, Sparre-Ulrich AH, Christensen M, Knop FK, Hartmann B, Holst JJ, Rosenkilde MM. (2016)
N-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor.
Br J Pharmacol, 173 (5): 826-38. [PMID:26572091]