PWT1-NPS   Click here for help

GtoPdb Ligand ID: 9167

Comment: PWT1-NPS is a tetrabranched derivative of human neuropeptide S (hNPS), which is suitable for in vitro and in vivo investigations [2]. Its structure consists of a chemical core linking 4 hNPS peptides. PWT stands for peptide welding technology (see patent WO2014161926 for further details [1]).
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1. Guerrini R, Salvadori S, Calo G. (2015)
Supramolecular aggregates comprising maleimido cores.
Patent number: WO2014161926. Assignee: Ufpeptides S.R.L.. Priority date: 05/04/2013. Publication date: 23/12/2015.
2. Ruzza C, Rizzi A, Malfacini D, Pulga A, Pacifico S, Salvadori S, Trapella C, Reinscheid RK, Calo G, Guerrini R. (2015)
In vitro and in vivo pharmacological characterization of a neuropeptide S tetrabranched derivative.
Pharmacol Res Perspect, 3 (1): e00108. [PMID:25692025]