GtoPdb Ligand ID: 9778

Synonyms: ARGX-110 | ARGX110 | clone 41D12
Compound class: Antibody
Comment: Cusatuzumab (ARGX-110) is a highly potent, afucosylated, humanized IgG1 anti-CD70 antibody being investigated for potential against solid and hematological tumours [2].
1. Silence K. (2010)
Single domain VHH antibodies against von Willebrand factor.
Patent number: US7807162 B2. Assignee: Ablynx N.V.. Priority date: 20/05/2006. Publication date: 05/10/2010.
2. Silence K, Dreier T, Moshir M, Ulrichts P, Gabriels SM, Saunders M, Wajant H, Brouckaert P, Huyghe L, Van Hauwermeiren T et al.. (2014)
ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade.
MAbs, 6 (2): 523-32. [PMID:24492296]