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Synonyms: mANP | mutant atrial natriuretic peptide
Compound class:
Peptide or derivative
Comment: This is a naturally occurring variant of human atrial natriuretic peptide (ANP) [1]. It is a fusion protein that contains the full 28 amino acids of ANP plus a 12 amino acid C-terminal extension. In comparison to normal ANP this longer peptide exhibits enhanced blood pressure-lowering, renal-enhancing, and aldosterone-suppressing actions in vivo.
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Peptide Sequence  |
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| SLRRSSCFGGRMDRIGAQSGLGCNSFRYRITAREDKQGWA | |
| Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-Arg-Ile-Thr-Ala-Arg-Glu-Asp-Lys-Gln-Gly-Trp-Ala | |
