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Synonyms: DACRA | KBP 066 | KBP066
Compound class:
Peptide
Comment: KBP-066 is a Dual Amylin and Calcitonin Receptor Agonist (DACRA), which are a class of peptide, which distinguish themselves from amylin agonists as they activate both the amylin receptor and the calcitonin receptor in a prolonged fashion.
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Peptide Sequence  |
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| Ac-CSNLSTCXLGRLSQDLHRLQTYPKTDVGANAP-NH2 | |
| Ac-Cys-Ser-Asn-Leu-Ser-Thr-Cys-X-Leu-Gly-Arg-Leu-Ser-Gln-Asp-Leu-His-Arg-Leu-Gln-Thr-Tyr-Pro-Lys-Thr-Asp-Val-Gly-Ala-Asn-Ala-Pro-NH2 | |
| Chemical Modification | |
| KBP-066 consists of an NH2-terminal acetyl group (Ac), an COOH-terminal amide group, and a 2-aminoisobutyric acid modification symbolized by an X. | |
