Synonyms: AZP-531 | AZP531 | Cyclo(des-acyl ghrelin(6-13)) | Des-acyl ghrelin
Compound class:
Peptide or derivative
Comment: Livoletide (AZP-531) is a first-in-class analogue of unacylated ghrelin (UAG) [2]. The exact mechanism of action is still unclear. When UAG is co-administered with ghrelin it is reported to act either as a functional antagonist or is acting via another receptor [2,4]. Other studies suggest that UAG is a full agonist [3].
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Peptide Sequence | |
(cyclo)-RVQSPEHQ-(cyclo) | |
cyclo[Arg-Val-Gln-Ser-Pro-Glu-His-Gln] |
HELM Notation | |
PEPTIDE1{R.V.Q.S.P.E.H.Q}$PEPTIDE1,PEPTIDE1,8:R2-1:R1$$$ |
Download 2D Structure | |
Canonical SMILES | Download |
Isomeric SMILES | Download |
InChI standard identifier | Download |
InChI standard key | Download |
Molecular structure representations generated using Open Babel