FGF-18   Click here for help

GtoPdb Ligand ID: 10974

Compound class: Endogenous peptide in human, mouse or rat
Comment: Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.
Species: Human
Peptide Sequence Click here for help
EENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLGRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFY
LCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQPELQK
PFKYTTVTKRSRRIRPTHPA
Selected 3D Structures
PDB Id: 4CJM
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
Disulphide bond between Cys109 and Cys127.