Synonyms: IPL-344
Compound class:
Peptide or derivative
Comment: IPL344 is a lead candidate for the treatment of ALS. It is a heptapeptide that acts to reactivate the PI3K-Akt pathway that is impaired in ALS motor neurons and muscles. IPL344 is administered intravenously. An oral Akt activator for ALS (IPL699) is included in Immunity Pharma's preclinical development pipeline.
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Peptide Sequence | |
H-LPPLPYP-OH | |
H-Leu-Pro-Pro-Leu-Pro-Tyr-Pro-OH |
HELM Notation | |
PEPTIDE1{L.P.P.L.P.Y.P}$$$$ |
Download 2D Structure | |
Canonical SMILES | Download |
Isomeric SMILES | Download |
InChI standard identifier | Download |
InChI standard key | Download |
Molecular structure representations generated using Open Babel