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Compound class:
Peptide or derivative
Comment: Synthetic analogue of human neuropeptide Y
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
Peptide Sequence  |
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| APLEPVYPGDNATPEQMARYYSALRHYINLAXRQRY | |
| Ala-Pro-Leu-Glu-Pro-Val-Tyr-Pro-Gly-Asp-Asn-Ala-Thr-Pro-Glu-Gln-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ala-Aib-Arg-Gln-Arg-Tyr-NH2 | |
| Chemical Modification | |
| Isoleucine at position 31 of the natural NPY sequence and threonine at position 32 are replaced by alanine and α-aminoisobutyric acid respectively. The first 17 residues in the amino acid sequence for NPY are replaced by thre first 17 residues from human PP | |
