inhibin βA   Click here for help

GtoPdb Ligand ID: 5006

Synonyms: activin βA | activin beta-A chain | erythroid differentiation factor (EDF) | follicle-stimulating hormone-releasing protein
Compound class: Endogenous peptide in human, mouse or rat
Species: Human
Is a component of
inhibin A
activin A
activin AB
Peptide Sequence Click here for help
GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSC
CVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS
Selected 3D Structures
PDB Id: 1nys
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
Forms a heterodimer with either inhibin alpha chain (forming inhibin A) or inhibin beta-B (forming activin AB). The third form of the active peptide is a homodimer of two beta-A chains forming activin-A. Interchain disulphide bond formation between cysteine residues at position 80. Disulphide bonds between cysteine residues at positions 4 and 12; 11 and 81, 40 and 113, and 44 and 115