brontictuzumab   Click here for help

GtoPdb Ligand ID: 11361

Synonyms: OMP-52M51 | OMP52M51
Compound class: Antibody
Comment: Brontictuzumab (OMP-52M51) is a fully human anti-NOTCH1 monoclonal antibody [4-5]. It was developed by OncoMed Pharmaceuticals. Peptide sequence analysis reveals that the heavy and light chains that make up brontictuzumab are claimed in Oncomed patent US20140011271A1 [3]. The heavy chain is SEQ ID NO:22 (52M51-H4), and the light chain is SEQ ID NO:26 (2M51L3), making the brontictuzumab structure 52M51H4L3.
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Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
9982 brontictuzumab
Synonyms Click here for help
OMP-52M51 | OMP52M51
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 492
Other databases
GtoPdb PubChem SID 440816730
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