bradykinin   Click here for help

GtoPdb Ligand ID: 649

Synonyms: BK | kallidin I | kinin 9
Comment: The rat, mouse and human sequences are identical.
Species: Human, Mouse, Rat
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2D Structure
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Canonical SMILES OCC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)O)CCCN=C(N)N)Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C1CCCN1C(=O)C1CCCN1C(=O)C(CCCN=C(N)N)N
Isomeric SMILES OC[C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCN=C(N)N)Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)N
InChI InChI=1S/C50H73N15O11/c51-32(16-7-21-56-49(52)53)45(72)65-25-11-20-39(65)47(74)64-24-9-18-37(64)43(70)58-28-40(67)59-34(26-30-12-3-1-4-13-30)41(68)62-36(29-66)46(73)63-23-10-19-38(63)44(71)61-35(27-31-14-5-2-6-15-31)42(69)60-33(48(75)76)17-8-22-57-50(54)55/h1-6,12-15,32-39,66H,7-11,16-29,51H2,(H,58,70)(H,59,67)(H,60,69)(H,61,71)(H,62,68)(H,75,76)(H4,52,53,56)(H4,54,55,57)/t32-,33-,34-,35-,36-,37-,38-,39-/m0/s1
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
IUPAC Name Click here for help
(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2S)-1-[(2S)-1-[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Synonyms Click here for help
BK | kallidin I | kinin 9
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
KNG1 kininogen 1 Human kininogen-1 precursor alpha-2-thiol proteinase inhibitor, BDK, bradykinin, kininogen, KNG
Kng1 kininogen 1 Mouse kininogen-1 precursor H-kininigen, L-kininogen
Kng2 kininogen 2 Rat kininogen-1 precursor alpha-1-MAP, kininogen, kininogen 1, kininogen 1, variant 1, KINKG, KINKH, KINT1G, K-kininogen, differential splicing leads to HMW Kngk, Kng, Kng1, Kng1_v1, Kngk, Kngt, Kngt1, Kng_v1, LMW T-kininogen I, major acute phase protein, Map1, MGC93589, RATKINKG, RATKINKH, RATKINT1G, RATTKG6, thiostatin, Tkg, TKG6, T-kininogen, T-kininogen 1, T-kininogen I, T-kininogen see also D11Elh1 and D11Mit8
Database Links Click here for help
ChEMBL Ligand CHEMBL406291
GtoPdb PubChem SID 135651637
PubChem CID 439201
Search Google for chemical match using the InChIKey QXZGBUJJYSLZLT-FDISYFBBSA-N
Search Google for chemicals with the same backbone QXZGBUJJYSLZLT
Search UniChem for chemical match using the InChIKey QXZGBUJJYSLZLT-FDISYFBBSA-N
Search UniChem for chemicals with the same backbone QXZGBUJJYSLZLT
UniProtKB P01042 (Hs), O08677 (Mm), P08934 (Rn)
Wikipedia Bradykinin

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Cat. No. 3004