- Advanced search
- Immuno Portal
- Malaria Portal
Synonyms: MDX-1103 | MEDI-545 | MEDI545
Compound class: Antibody
Comment: Sifalimumab is a monoclonal antibody targeting interferon α1 (IFNA1), that was developed by the MedImmune subsidiary of AstraZeneca as a treatment for systemic lupus erythematosus (SLE). Development of sifalimumab was terminated and MedImmune concentrated on their alternative anti-IFNα agent anifrolumab.
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. Sequence BLAST using the heavy and light chain variable regions of sifalimumab provides 100% matches to sequences patented with application US7741449 . The sequence matches identify sifalimumab as clone 13H5 in the patent.
|International Nonproprietary Names
|MDX-1103 | MEDI-545 | MEDI545
|GtoPdb PubChem SID
|Search PubMed clinical trials
|Search PubMed titles
|Search PubMed titles/abstracts