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Synonyms: AMG 157 | AMG-157 | MEDI-9929 | MEDI9929 | tezepelumab-ekko | Tezspire®
tezepelumab is an approved drug (FDA (2021), ENA (2022))
Compound class:
Antibody
Comment: Tezepelumab is a fully human IgG2λ monoclonal antibody, that is a potential first-in-class agent that blocks the epithelial-cell-derived cytokine thymic stromal lymphopoietin (TSLP- which is an upstream modulator of multiple inflammatory pathways). It is being investigated for its immunomodulatory action.
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Classification  |
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| Compound class | Antibody |
| Approved drug? | Yes (FDA (2021), ENA (2022)) |
| International Nonproprietary Names |
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| INN number | INN |
| 10172 | tezepelumab |
| Synonyms |
| AMG 157 | AMG-157 | MEDI-9929 | MEDI9929 | tezepelumab-ekko | Tezspire® |
| Database Links |
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| Specialist databases | |
| IMGT/mAb-DB | 573 |
| Other databases | |
| GtoPdb PubChem SID | 310264714 |
| Search PubMed clinical trials | tezepelumab |
| Search PubMed titles | tezepelumab |
| Search PubMed titles/abstracts | tezepelumab |
